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Study identifier: NCT05051254 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Respiratory Muscles and Work of Breathing in Children

Condition: Neuromuscular Diseases · Congenital Diaphragmatic Hernia · Lung Diseases  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhaseNA
Planned participants550
Who can joinAll sexes, 0 Years to 17 Years
Healthy volunteersNo

About this study

Respiratory muscle testing allows a quantitative assessment of inspiratory and expiratory muscles in children of any age with primary or secondary respiratory muscle impairment, in order to better understand the pathophysiology of respiratory impairment and guide therapeutic management. The use of an invasive technique (esogastric probe) makes it possible to specifically explore the diaphragm, the accessory inspiratory muscles and the expiratory muscles in order to detect dysfunction or paralysis of these muscles, and to estimate the work of breathing in order to better guide the respiratory management. The primary objective of the study is to evaluate the respiratory effort in children with primary or secondary impairment of the respiratory muscles during spontaneous breathing or during mechanical ventilation.

This description comes directly from the study's public registry record.

Talk to the study team

Brigitte FAUROUX, MD, PhD  ·  1 71 19 60 92  ·  brigitte.fauroux@aphp.fr

Hélène MOREL  ·  1 71 19 63 46  ·  helene.morel@aphp.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Hôpital Necker-Enfants MaladesParis, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05051254