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Study identifier: NCT05049889 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Screening for Individual Susceptibility Factors to Immersion Pulmonary Edema

Condition: Pulmonary Edema  ·  Sponsor: Direction Centrale du Service de Santé des Armées

PhaseNA
Planned participants63
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersYes

About this study

Immersion Pulmonary Edema (IPE) is a relatively new form of hemodynamic pulmonary edema. The number of cases has been increasing over the last ten years and it has become the second most common cause of hospitalization for military divers, after decompression sickness. The pathophysiological mechanisms of IPE are not completely known. Its occurrence is linked to a combination of factors related to the environmental constraints of diving, as well as to the diver's equipment. The main external factors are increased hydrostatic pressure, cold, intense effort and emotional stress. The impact of internal factors is not known. At this time, no severe forms of IPE have been identified in the military. However, it is important to identify this pathology at an early stage, even if the signs appear minor, because the continuation of underwater activity can significantly worsen the clinical picture. The risk of recurrence (greater than 15%) could result in a severe or even lethal accident.

This description comes directly from the study's public registry record.

Talk to the study team

CASTAGNA Olivier, MD, PhD  ·  483162830  ·  olivier.castagna@intradef.gouv.fr

Always discuss trial participation with your own doctor first.

Locations (2)

Equipe Résidente de Recherche Subaquatique OpérationnelleToulon, FranceRecruiting
Hôpital d'Instruction des Armées Sainte-AnneToulon, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05049889