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Study identifier: NCT05047133 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Early Administration of TXA in Adult Hip Fractures

Condition: Postoperative Blood Loss  ·  Sponsor: Ascension Health

PhasePhase 2/Phase 3
Planned participants170
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

This is a prospective clinical study designed to assess blood loss in intracapsular and extracapsular hip fractures undergoing operative fixation at a Level II trauma center. It is well established in the orthopedic literature that tranexamic acid (TXA) decreases blood loss and need for postoperative blood transfusion in hip fracture patients as well as total joint arthroplasty patients. A typical dosing pattern, and the dosing pattern employed at our institution, is 1 gram IV infused prior to incision followed by 1 gram IV infused at the time of wound closure.

This description comes directly from the study's public registry record.

Talk to the study team

Jacob Hinkley, DO, MS  ·  810-606-5669  ·  jacob.hinkley2@ascension.org

Jacob Lytle, DO  ·  810-606-5669  ·  jacob.lytle@ascension.org

Always discuss trial participation with your own doctor first.

Locations (1)

Ascension Genesys HospitalGrand Blanc, Michigan, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05047133