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Study identifier: NCT05041556 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Strengthening the Evidence for Policy on the RTS,S/AS01 Malaria Vaccine

Condition: Malaria  ·  Sponsor: Kintampo Health Research Centre, Ghana

PhaseN/A
Planned participants9280
Who can joinAll sexes, 6 Months to 59 Months
Healthy volunteersNo

About this study

The ongoing Malaria Vaccine Pilot Evaluation (MVPE) is being conducted in Ghana, Malawi and Kenya through community and sentinel hospital surveillance systems and a series of household surveys (to measure vaccine coverage). The Malaria Vaccine Pilot Evaluation-Case Control (MVPE-CC) registered here as observational study is embedded within MVPE comprising case-control studies of clinical and mortality outcomes. Each case will require four controls, and caregiver informed consent will be required prior to study activities. These observational case control studies will measure as complementary information to what is being collected through MVPE: 1. Safety among children who received the malaria vaccine, with focus on cerebral malaria, meningitis and severe malaria 2. The impact of the malaria vaccine on all-cause mortality for boys and girls, AND 3. Promote use of case-control approaches by Expanded Programmes on Immunization (EPI) and malaria control programmes.

This description comes directly from the study's public registry record.

Talk to the study team

Thomas Gyan  ·  0208398541  ·  thomas.gyan@kintampo-hrc.org

Always discuss trial participation with your own doctor first.

Locations (4)

Kintampo Health Research CentreKintampo, GhanaRecruiting
African Research Collaboration for Health LimitedNairobi, KenyaRecruiting
Kenya Medical Research Institute (KEMRI)Nairobi, KenyaRecruiting
College of Medicine, University of MalawiBlantyre, MalawiRecruiting

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Source record: clinicaltrials.gov/study/NCT05041556