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Study identifier: NCT05035836 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase 2 Single-Arm Open-Label Pilot Trial Evaluating Zanidatamab (ZW25) in Patients With Early Stage HER2/Neu Positive (HER2+) Breast Cancer (BC)

Condition: Breast Cancer · HER2-positive  ·  Sponsor: M.D. Anderson Cancer Center

PhasePhase 2
Planned participants20
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 2, single-site, single-arm open-label trial of zanidatamab in patients with early stage, low risk HER2+ BC. The primary objective is to determine the efficacy of zanidatamab for patients with early stage HER2/neu positive (HER2+) breast cancer (BC) as determined by pathologic complete response (pCR) .

This description comes directly from the study's public registry record.

Talk to the study team

Vicente Valero  ·  713-563-0751  ·  vvalero@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (1)

M D Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05035836