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Study identifier: NCT05027711 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Magnetic Resonance-guided Adaptive Stereotactic Body Radiotherapy for Hepatic Metastases

Condition: Hepatic Metastasis  ·  Sponsor: University Hospital Heidelberg

PhasePhase 2
Planned participants90
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Stereotactic body radiotherapy (SBRT) is an established local treatment method for patients with hepatic oligometastases. Liver metastases often occur in close proximity to radiosensitive organs at risk (OARs). This limits the possibility to apply sufficiently high doses needed for optimal local control. MR-guided radiotherapy (MRgRT) is expected to hold potential to improve hepatic SBRT by offering superior soft-tissue contrast for enhanced target identification as well as the benefit of daily real-time adaptive treatment. The MAESTRO trial therefore aims to assess the potential advantages of adaptive, gated MR-guided SBRT (MRgSBRT) compared to conventional SBRT at a standard linac using an ITV (internal target volume) approach (ITV-SBRT).

This description comes directly from the study's public registry record.

Talk to the study team

Jakob Liermann, PD Dr  ·  +496221 56  ·  jakob.liermann@med.uni-heidelberg.de

Always discuss trial participation with your own doctor first.

Locations (1)

University Hospital of Heidelberg, Radiation OncologyHeidelberg, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT05027711