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Study identifier: NCT05024552 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Vyxeos Plus Gilteritinib in Relapsed or Refractory, FLT3-Mutated AML

Condition: Acute Myeloid Leukemia With FLT3/ITD Mutation  ·  Sponsor: H. Lee Moffitt Cancer Center and Research Institute

PhasePhase 1
Planned participants22
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study combines vyxeos and gilteritinib in patients with relapsed or refractory FLT3-mutated acute myeloid leukemia. Vyxeos and gilteritinib will be given as induction therapy. Those patients entering a complete remission or a complete remission with incomplete blood count recovery will be allowed to proceed to consolidation therapy with vyxeos and gilteritinib. Those patients who do not proceed to an allogeneic stem cell transplant for any reason are able to enter the maintenance phase of this trial using daily gilteritinib

This description comes directly from the study's public registry record.

Talk to the study team

Jhada-Kai Hunter  ·  813-745-0286  ·  Jhada-Kai.Hunter@moffitt.org

Always discuss trial participation with your own doctor first.

Locations (1)

Moffitt Cancer CenterTampa, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05024552