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Study identifier: NCT05019885 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Efficacy of a Subanesthetic Doses of IV Ketamine in the Treatment Drug Resistant Epilepsy

Condition: Drug Resistant Epilepsy · Medically Refractory Epilepsy · Refractory Epilepsy  ·  Sponsor: Madeline Fields

PhasePhase 2
Planned participants8
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Ketamine is a medication that came into clinical practice in the 1960's. Ketamine is used as an anesthetic and to provide pain relief. Recently, Ketamine was approved to treat drug resistant depression using subanesthetic doses. In the hospital setting, intravenous anesthetic dosages are used to treat unrelenting seizures known as status epilepticus in comatose patients. Ketamine in subanesthetic doses has not been tried as a treatment for medication resistant seizures in the outpatient setting. This study would like to examine the effectiveness of subanesthetic ketamine in outpatients who suffer from drug resistant epilepsy.

This description comes directly from the study's public registry record.

Talk to the study team

Onome Eka, MBBS MPH  ·  212-241-8861  ·  onome.eka@mssm.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Mount Sinai HospitalNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05019885