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Study identifier: NCT05019846 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

SRT Versus SRT+ADT in Prostate Cancer

Condition: Prostate Cancer  ·  Sponsor: Marco Lorenzo Bonu

PhasePhase 3
Planned participants310
Who can joinMale, 18 Years to 80 Years
Healthy volunteersNo

About this study

To clarify the role of short-term Androgen deprivation therapy (ADT) in the context of intermediate unfavorable and a subclass of high-risk patients treated with prostate Stereotactic radiotherapy (SRT). In intermediate unfavorable risk group, when choosing standard external beam radiotherapy, short term ADT is superior in terms of biochemical disease free survival (bDFS) to EBRT alone. In high risk disease, results of the combination therapy are even more clear. Prostate SRT has been endorsed as option for primary radical treatment for prostate cancer. In such patients, the benefit of ADT is still unknown and the decision is left to clinical judgement. For these reasons, it seems to be relevant to propose a randomized, open label, phase III clinical trial of prostate SBRT + 6 months ADT versus prostate SBRT alone in intermediate unfavorable and a subgroup of high risk prostate cancer patients.

This description comes directly from the study's public registry record.

Talk to the study team

Marco Lorenzo Bonù, MD  ·  +390303995285  ·  marco.bonu@unibs.it

Always discuss trial participation with your own doctor first.

Locations (1)

ASST Spedali Civili of BresciaBrescia, BS, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT05019846