Condition: Pacemaker DDD · Heart Block · Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre
High burden right ventricular (RV) pacing has been shown to increase cardiovascular mortality, incidence of heart failure (HF), worsen left ventricular (LV) function and accelerate the development of atrial fibrillation (AF). High percentage ventricular pacing and wider paced QRS in the setting of normal baseline LV ejection fractions have consistently been shown to be independent risk factors for pacing-induced cardiomyopathy. Left bundle branch pacing (LBBP) has emerged as a potential alternative pacing mechanism that may avoid LV dyssynchrony and pacing-induced LV dysfunction by mimicking native electrical conduction.
This description comes directly from the study's public registry record.
Jacqueline Joza, MD MSc · 514-934-1934 · jacqueline.joza@gmail.com
Fiorella Rafti, PhD · 514-934-1934 · fiorella.rafti@mail.mcgill.ca
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| McGill University Health Centre-Research Institute | Montreal, Quebec, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05015660