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Study identifier: NCT05011422 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Haploidentical Hematopoietic Stem Cell Transplantation With Ex Vivo TCR Alpha/Beta and CD19 Depletion in Pediatric Hematologic Malignancies

Condition: Pediatric Hematologic Malignancies  ·  Sponsor: Washington University School of Medicine

PhasePhase 1
Planned participants50
Who can joinAll sexes, N/A to 30 Years
Healthy volunteersNo

About this study

This single arm pilot phase I study with safety run-in is designed to estimate the safety and efficacy of a familial mismatched or haploidentical hematopoietic stem cell transplantation (haplo-HSCT) using a novel graft modification technique (selective αβ-TCR and CD19 depletion).

This description comes directly from the study's public registry record.

Talk to the study team

Thomas Pfeiffer, M.D.  ·  314-273-2070  ·  pthomas@wustl.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Washington University School of MedicineSt Louis, Missouri, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05011422