Condition: Metastatic Prostate Cancer · Sponsor: VA Office of Research and Development
This study will determine whether the presence of DNA repair deficiency in the form of alterations in the genes ATM, CDK12 or CHEK2 predicts for a high likelihood of responding to the use of intermittent high dose testosterone. This therapy may result in responses in tumors which are genetically unstable because of DNA repair deficiency and this is a prospective study to test that hypothesis
This description comes directly from the study's public registry record.
Robert B Montgomery, MD · (206) 277-6878 · Robert.Montgomery@va.gov
Elahe Mostaghel, MD · (206) 762-1010 · emostagh@fhcrc.org
Always discuss trial participation with your own doctor first.
| Rocky Mountain Regional VA Medical Center, Aurora, CO | Aurora, Colorado, United States | Recruiting |
| VA Connecticut Healthcare System West Haven Campus, West Haven, CT | West Haven, Connecticut, United States | Recruiting |
| North Florida/South Georgia Veterans Health System, Gainesville, FL | Gainesville, Florida, United States | Recruiting |
| Orlando VA Medical Center, Orlando, FL | Orlando, Florida, United States | Recruiting |
| Atlanta VA Medical and Rehab Center, Decatur, GA | Decatur, Georgia, United States | Recruiting |
| Robley Rex VA Medical Center, Louisville, KY | Louisville, Kentucky, United States | Recruiting |
| Kansas City VA Medical Center, Kansas City, MO | Kansas City, Missouri, United States | Recruiting |
| St. Louis VA Medical Center John Cochran Division, St. Louis, MO | St Louis, Missouri, United States | Recruiting |
| Durham VA Medical Center, Durham, NC | Durham, North Carolina, United States | Recruiting |
| Salisbury W.G. (Bill) Hefner VA Medical Center, Salisbury, NC | Salisbury, North Carolina, United States | Recruiting |
| VA Portland Health Care System, Portland, OR | Portland, Oregon, United States | Recruiting |
| Ralph H. Johnson VA Medical Center, Charleston, SC | Charleston, South Carolina, United States | Recruiting |
+ 5 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05011383