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Study identifier: NCT05010148 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Clinical Trial of Intravenous Lidocaine After Spinal Surgery to Prevent Delirium and Reduce Pain

Condition: Postoperative Delirium · Postoperative Pain · Spinal Fusion  ·  Sponsor: University of California, San Francisco

PhasePhase 3
Planned participants278
Who can joinAll sexes, 60 Years to no upper limit
Healthy volunteersYes

About this study

Postoperative delirium is one of the most frequent adverse events following elective non-cardiac surgery and is associated with cognitive impairment at discharge, as well as in-hospital and long-term mortality, however, despite being a well-recognized problem there is a dearth of effective interventions for prevention and management. A modifiable risk factor associated with postoperative delirium is poor postoperative pain control, and by improving the pain regimen the investigators may be able to decrease the incidence and/or severity of postoperative delirium. In this study, the investigators seek to study whether a postoperative intravenous infusion of lidocaine, known to improve pain control in other contexts, can decrease the risk of postoperative delirium and other opioid-related side effects, following major reconstructive spinal surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Marc A Buren, MD  ·  415-476-8369  ·  marc.buren@ucsf.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of California, San FranciscoSan Francisco, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05010148