← Eichor
Study identifier: NCT05007132 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Trifluridine/ Tipiracil Plus Panitumumab Versus Trifluridine/ Tipiracil Plus Bevacizumab as First-line Treatment of Metastatic Colorectal Cancer

Condition: Metastatic Colorectal Cancer  ·  Sponsor: Dominik Paul Modest

PhasePhase 2
Planned participants153
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

FIRE-8 is a prospective, randomized, open label, multicenter phase II clinical trial. To evaluate the effecacy of trifluridine / tipiracil and panitumumab (Arm A) compared to trifluridine / tipiracil and bevacizumab (Arm B), participants will be randomly assigned to either Arm A or Arm B for the treatment of metastatic colorectal cancer. The primary objectives of this study is to compare the effecacy of treatment with trifluridine / tipiracil plus panitumumab versus trifluridine / tipiracil plus bevacizumab.

This description comes directly from the study's public registry record.

Talk to the study team

Dominik Paul Modest, Prof.  ·  +49 30 450 553840  ·  dominik.modest@charite.de

Sebastian Stintzing, Prof.  ·  +49 30 450 513002  ·  sebastian.stintzing@charite.de

Always discuss trial participation with your own doctor first.

Locations (1)

Charité - Universitätsmedizin BerlinBerlin, GermanyRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05007132