Condition: Advanced Cancer · Metastatic Solid Tumor · Sponsor: Memorial Sloan Kettering Cancer Center
This study will test the safety of the study drug, repotrectinib, in combination with chemotherapy (irinotecan and temozolomide) in children and young adults who have advanced or metastatic solid tumors. We researchers will try to find the highest dose of the study drug that causes few or mild side effects in study participants. When the researchers find this dose, we will evaluate it in a different group of participants to find out whether repotrectinib in combination with chemotherapy is an effective treatment for children and young adults who have advanced/metastatic solid tumors. Another purpose of the study is to look at the way the body absorbs, distributes, and gets rid of repotrectinib.
This description comes directly from the study's public registry record.
Emily Slotkin, MD · 1-833-675-5437 · slotkine@mskcc.org
Fiorella Iglesias Cardenas, MD,MS · 1-833-675-5437
Always discuss trial participation with your own doctor first.
| Memorial Sloan Kettering Cancer Center (All Protocol Activities) | New York, New York, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05004116