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Study identifier: NCT05000892 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neoadjuvant Sintilimab in Combination With Carboplatin and Nab-paclitaxel in Untreated Salivary Gland Malignant Neoplasms

Condition: Salivary Gland Malignant Neoplasms · Salivary Gland Tumors  ·  Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

PhasePhase 2
Planned participants15
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This proposed study will evaluate the efficacy and safety of preoperative administration Sintilimab combined with nab-paclitaxel and carboplatin in salivary gland malignant neoplasms who are about to undergo surgery. Monoclonal antibodies, such as Sintilimab, may interfere with the ability of tumor cells to grow and spread. Drugs used in chemotherapy, such as carboplatin and nab-paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial will be helpful for comprehensive exploratory characterization of tumor immune microenvironment and circulating immune cells in these patients.

This description comes directly from the study's public registry record.

Talk to the study team

Song Fan, Doctor degrees  ·  020-81332477  ·  fansong2@mail.asysu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Sun Yat-sen Memorial HospitalGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05000892