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Study identifier: NCT04998916 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience

Condition: Alcohol Use Disorder · Alcohol Drinking · Substance Use  ·  Sponsor: Medical University of South Carolina

PhaseNA
Planned participants86
Who can joinAll sexes, 21 Years to 65 Years
Healthy volunteersNo

About this study

The purpose of this study is to develop transcranial magnetic stimulation (TMS), specifically TMS at a frequency known as theta burst stimulation (TBS), to see how it affects the brain and changes the brain's response to alcohol-related pictures. TMS and TBS are stimulation techniques that use magnetic pulses to temporarily excite specific brain areas in awake people (without the need for surgery, anesthetic, or other invasive procedures). TBS, which is a form of TMS, will be applied over the medial prefrontal cortex, (MPFC), which has been shown to be involved with drinking patterns and alcohol consumption. This study will test whether TBS can be used as an alternative tool to reduce the desire to use alcohol and reducing the brain's response to alcohol-related pictures.

This description comes directly from the study's public registry record.

Talk to the study team

Lisa M McTeague  ·  842-792-8274  ·  mcteague@musc.edu

Rhia Walton  ·  842-792-8274  ·  waltonrh@musc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Medical University of South CarolinaCharleston, South Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04998916