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Study identifier: NCT04998396 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of AAV9 Gene Therapy in Participants With Canavan Disease (CANaspire Clinical Trial)

Condition: Canavan Disease  ·  Sponsor: Aspa Therapeutics

PhasePhase 1/Phase 2
Planned participants26
Who can joinAll sexes, N/A to 30 Months
Healthy volunteersNo

About this study

The main objective of this trial is to evaluate the safety, tolerability, and pharmacodynamic activity of BBP-812, an investigational AAV9-based gene therapy, in pediatric participants with Canavan disease.

This description comes directly from the study's public registry record.

Talk to the study team

Alicia Gomez  ·  833-764-2267 or 617-861-4617  ·  CANaspire@aspatx.com

clinicaltrials@aspatx.com

Always discuss trial participation with your own doctor first.

Locations (4)

UCSF Benioff Children's Hospital OaklandOakland, California, United StatesRecruiting
Ann & Robert H. Lurie Children's Hospital of ChicagoChicago, Illinois, United StatesRecruiting
Massachusetts General Hospital (MGH); Center for Rare Neurological Diseases (CRND)Boston, Massachusetts, United StatesRecruiting
Weill Cornell Medicine; Division of Pediatric NeurologyNew York, New York, United StatesCompleted

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Source record: clinicaltrials.gov/study/NCT04998396