Condition: PTEN-Altered Advanced Solid Tumors and HER2 Negative Breast Cancer · Sponsor: Deborah Doroshow
Leflunomide in patients with PTEN-Altered advanced solid tumors or HER2 negative breast cancer. Phase 1A objectives are to determine the safety, tolerability, and the MTD of leflunomide in patients with PTEN-Altered advanced solid malignancies and HER2 negative breast cancer. Phase 1B objective is to assess preliminary evidence of clinical activity of leflunomide in these patient populations.
This description comes directly from the study's public registry record.
Deborah Doroshow, MD, PhD · (212) 241-5615 · deborah.doroshow@mssm.edu
Natalie Lucas, DNP · natalie.lucas@mssm.edu
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| Icahn School of Medicine at Mount Sinai | New York, New York, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04997993