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Study identifier: NCT04997317 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Treatment of Recurrent or Progressive Meningiomas With the Radiolabelled Somatostatin Antagonist 177Lu-satoreotide

Condition: Meningioma  ·  Sponsor: University Hospital, Basel, Switzerland

PhasePhase 1/Phase 2
Planned participants18
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Meningiomas are known to be the most frequent intracranial neoplasms and account for approx. 25-33% of all intracranial tumours.Targeted radionuclide therapy with radiolabelled somatostatin analogues, also called Peptide Receptor Radionuclide Therapy (PRRT), has proven to be an effective treatment in metastatic intestinal neuroendocrine tumours and is currently used in advanced, recurrent or progressive meningiomas with promising results. In this study, the therapeutic index of a standard and newly developed radiolabelled somatostatin antagonist will be evaluated and compared in PRRT. In a second step, safety and efficacy of the latter will be assessed.

This description comes directly from the study's public registry record.

Talk to the study team

Damian Wild, Prof. Dr. med.  ·  +41 61 328 6683  ·  damian.wild@usb.ch

Dominik Cordier, PD Dr. med.  ·  +41 61 55 65 642  ·  dominik.cordier@usb.ch

Always discuss trial participation with your own doctor first.

Locations (1)

University Hospital Basel, Department of NeurosurgeryBasel, Canton of Basel-City, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT04997317