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Study identifier: NCT04990609 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

EUS-RFA PANCARDINAL-1 Trial

Condition: Pancreatic Ductal Adenocarcinoma (PDAC)  ·  Sponsor: The University of Texas Health Science Center, Houston

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The objectives of this study are to determine the feasibility, tolerability, and treatment effect of endoscopic ultrasound (EUS) radiofrequency ablation (RFA) plus standard-of-care neoadjuvant chemotherapy (NAC) in the treatment of pancreatic ductal adenocarcinoma (PDAC). Endoscopic ultrasound (EUS) radiofrequency ablation (RFA) and neoadjuvant chemotherapy (NAC) will be performed before tumor resection surgery, with the goal of shrinking a tumor or stopping the spread of cancer so that surgery might be less invasive and more effective.

This description comes directly from the study's public registry record.

Talk to the study team

Sofia C Colon, BS  ·  713-500-6658  ·  Sofia.C.Colon@uth.tmc.edu

Nirav Thosani, MD  ·  713-486-1350  ·  pancreasresearch@uth.tmc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Memorial Hermann HospitalHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04990609