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Study identifier: NCT04990102 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase IB/II of CPX-351 for Relapse Prevention in AML

Condition: Acute Myeloid Leukemia (AML) in Remission  ·  Sponsor: Georgetown University

PhasePhase 1/Phase 2
Planned participants24
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase IB/II study with a 3+3 dose de-escalation study design. Patients will continue maintenance treatment with CPX-351 for 6 cycles on D1 and D3, as long as patient remains in CR. The dose de-escalation will be one dose given on D1 only, every 28 days pending toxicity. The maximum tolerated dose will be used for the phase II expansion portion of the study.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (3)

Georgetown Lombardi Comprehensive Cancer CenterWashington D.C., District of Columbia, United StatesRecruiting
John Theurer Cancer Center at Hackensack University Medical CenterHackensack, New Jersey, United StatesRecruiting
University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04990102