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Study identifier: NCT04987775 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

GWICTIC: NAC Mechanistic Study in Gulf War Veterans

Condition: Gulf War Syndrome  ·  Sponsor: Nova Southeastern University

PhaseEARLY_Phase 1
Planned participants170
Who can joinAll sexes, 47 Years to 70 Years
Healthy volunteersNo

About this study

This mechanistic study will test if NAC affects chronic oxidative stress and depletion of antioxidants in GWI participants. Blood specimen collection and neuroimaging will be used to determine whether NAC affects serum glutathione (GSH) concentration and oxidative stress in the CNS when compared to placebo.

This description comes directly from the study's public registry record.

Talk to the study team

Nancy Klimas, MD  ·  9542622855  ·  nklimas@nova.edu

Karen Kesler, PhD  ·  kkelser@rti.org

Always discuss trial participation with your own doctor first.

Locations (7)

VA Palo Alto Health Care System War Related Illness and Injury Study CenterPalo Alto, California, United StatesRecruiting
Nova Southeastern UniversityFort Lauderdale, Florida, United StatesRecruiting
Boston University Medical SchoolBoston, Massachusetts, United StatesActive Not Recruiting
VA New Jersey Health Care System War Related Illness and Injury Study CenterEast Orange, New Jersey, United StatesRecruiting
Weill Cornell Medical CollegeNew York, New York, United StatesActive Not Recruiting
RTI InternationalDurham, North Carolina, United StatesActive Not Recruiting
Michael E. DeBakey VA Medical CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04987775