Condition: PTSD · Sponsor: University Hospital, Toulouse
By age 18, roughly 8% of traumatized youth have met criteria for a diagnosis of PTSD, with numbers rising up to 40% in cases of sexual abuse and assault. To date there is no empirical support for the use of psychopharmacological interventions as treatment of pediatric PTSD. Trauma-focused psychotherapeutic/TFP approaches should be favored in childhood PTSD. However, when compared to active control conditions, TFP produced a mean effect size on child and adolescents population (g=0.83). Moreover, in therapies with a substantial exposure component, the intense and lengthy reexperiencing of the traumatic event results in a substantial proportion of participants dropping out. The reactivation of a previously consolidated memory can make it labile, subsequently requiring a re-stabilization of it called reconsolidation of the memory. Acting on these reconsolidation processes makes possible to interfere with the subsequent storage of this memory.
This description comes directly from the study's public registry record.
Philippe Birmes, PH · 05 34 55 75 00 · birmes.p@chu-toulouse.fr
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| Toulouse University Hospital | Toulouse, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04985344