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Study identifier: NCT04982965 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Brain Mechanisms Supporting Cannabis-induced Pain Relief

Condition: Sciatica · Lumbar Radiculopathy · Lower Back Pain  ·  Sponsor: University of California, San Diego

PhaseEARLY_Phase 1
Planned participants100
Who can joinAll sexes, 21 Years to 65 Years
Healthy volunteersYes

About this study

Chronic low back pain is a common and disabling condition that affects millions of people in the United States. Many people with chronic low back pain do not get enough relief from current treatments. Cannabis may help reduce pain, but researchers do not fully understand how it affects the brain in people with chronic pain. The purpose of this study is to examine how inhaled cannabis changes brain activity and reduces pain in people with chronic low back pain. Results from this study may help researchers better understand how cannabis works for pain and support the development of improved pain treatments.

This description comes directly from the study's public registry record.

Talk to the study team

Madelynn Meredith, BS  ·  619-431-1850  ·  mameredith@health.ucsd.edu

Yasmeen Esshaki, MA  ·  619-786-0375  ·  yesshaki@health.ucsd.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Center for Functional MRI - W.M.Keck BuildingLa Jolla, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04982965