Condition: Solid Tumor, Adult · Colorectal Cancer · Non Small Cell Lung Cancer · Sponsor: A2 Biotherapeutics Inc.
Objective: To collect information on how often a solid tumor cancer might lose the Human Leukocyte Antigen (HLA) by next generation sequencing and perform apheresis to collect and store an eligible participant's own T cells for future use to make CAR T-Cell therapy for their disease treatment. Design: This is a non-interventional, observational study to evaluate participants with solid tumors with a high risk of relapse for incurable disease. No interventional therapy will be administered on this study. Some of the information regarding the participant's tumor analysis may be beneficial to management of their disease. Participants that meet all criteria may be enrolled and leukapheresed (blood cells collected). The participant's cells will be processed and stored for potential manufacture of CAR T-cell therapy upon relapse of their cancer.
This description comes directly from the study's public registry record.
Clinical Trials · (310)431-9180 · ClinicalTrials@a2bio.com
Always discuss trial participation with your own doctor first.
| Banner Health | Gilbert, Arizona, United States | Recruiting |
| Mayo Clinic Hospital | Phoenix, Arizona, United States | Recruiting |
| City of Hope | Duarte, California, United States | Completed |
| University of California San Diego | La Jolla, California, United States | Recruiting |
| Stanford University | Palo Alto, California, United States | Recruiting |
| UCLA Medical Center | Santa Monica, California, United States | Recruiting |
| Mayo Clinic Jacksonville | Jacksonville, Florida, United States | Recruiting |
| Moffitt Cancer Center | Tampa, Florida, United States | Recruiting |
| Massachusetts General Hospital/Dana Farber Cancer Institute | Boston, Massachusetts, United States | Completed |
| Mayo Clinic Rochester | Rochester, Minnesota, United States | Recruiting |
| Washington University | St Louis, Missouri, United States | Recruiting |
| NYU Langone Medical Center | New York, New York, United States | Recruiting |
+ 4 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT04981119