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Study identifier: NCT04979078 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Photobiomodulation Therapy in the Management of Hand-foot Syndrome and Hand-foot Skin Reaction

Condition: Hand-foot Syndrome · Hand-foot Skin Reaction  ·  Sponsor: Jessa Hospital

PhaseNA
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Hand-foot syndrome (HFS) is a side effect of chemotherapy. HFS is characterized by redness, swelling, and pain on the palms of the hands and/or soles of the feet, which can progress to blistering. Hand-foot skin reaction (HFSR) refers to symptoms affecting the hands and/or feet associated with multikinase inhibitors (TKIs). HFS and HFSR are painful complications that can lead to compromised daily activities, sleep-wake disturbance and impaired mobility, eventually decreasing Quality of Life (QoL). Photobiomodulation therapy (PBMT) is a non-invasive therapy based on the application of visible and/or near-infrared light produced by a laser diode or a light-emitting diode. The scientifically proven biologic effects of PBM are improved wound healing, and a reduction in pain, inflammation, and oedema. The aim of this study is to evaluate the effectiveness of PBMT in the management of HFS and HFSR.

This description comes directly from the study's public registry record.

Talk to the study team

Jeroen Mebis, MD, PhD  ·  +32 11 33 72 21  ·  Jeroen.mebis@jessazh.be

Jolien Robijns, PhD  ·  +32 11 33 72 29  ·  jolien.robijns@uhasselt.be

Always discuss trial participation with your own doctor first.

Locations (2)

Hasselt UniversityHasselt, Limburg, BelgiumNot Yet Recruiting
Jessa Ziekenhuis VZWHasselt, Limburg, BelgiumRecruiting

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Source record: clinicaltrials.gov/study/NCT04979078