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Study identifier: NCT04977375 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma

Condition: Glioblastoma Multiforme  ·  Sponsor: Chirag G. Patil

PhasePhase 1/Phase 2
Planned participants10
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to assess the safety/tolerability/feasibility of pembrolizumab and radiation therapy before surgical resection in patients with recurrent glioblastoma as defined by treatment-related AEs and the number of patients who do not necessitate a delay in surgical resection, and to assess overall survival. The secondary objectives are to assess progression free survival, and to assess the T cell clonality, CD8 T cell activation and Tumor Infiltrating Lymphocyte (TIL) score after treatment

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trial Recruitment Navigator  ·  3104232133  ·  cancer.trial.info@cshs.org

Always discuss trial participation with your own doctor first.

Locations (1)

Cedars-Sinai Medical CenterLos Angeles, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04977375