← Eichor
Study identifier: NCT04973605 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma

Condition: Relapsed/Refractory Multiple Myeloma  ·  Sponsor: BeOne Medicines

PhasePhase 1/Phase 2
Planned participants246
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to assess the safety, tolerability, and efficacy of sonrotoclax as monotherapy and in various combinations in patients with relapsed/refractory (R/R) multiple myeloma (MM) and chromosomal translocation t(11;14). The study investigates sonrotoclax alone and in combination with dexamethasone and other agents, including carfilzomib, daratumumab, and pomalidomide.

This description comes directly from the study's public registry record.

Talk to the study team

BeOne Medicines  ·  1.877.828.5568  ·  clinicaltrials@beonemed.com

Always discuss trial participation with your own doctor first.

Locations (84)

University of Alabama At Birmingham HospitalBirmingham, Alabama, United StatesRecruiting
City of Hope National Medical CenterDuarte, California, United StatesRecruiting
City of Hope Irvine LennarIrvine, California, United StatesRecruiting
University of MiamiMiami, Florida, United StatesRecruiting
Emory University Winship Cancer CenterAtlanta, Georgia, United StatesRecruiting
University of Chicago Medical CenterChicago, Illinois, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesCompleted
Washington University School of MedicineSt Louis, Missouri, United StatesRecruiting
Hackensack University Medical CenterHackensack, New Jersey, United StatesRecruiting
Weill Cornell Medical College Newyork Presbyterian HospitalNew York, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer Center MskccNew York, New York, United StatesRecruiting
The James Cancer Hospital and Solove Research Institute At Ohio State UniversityColumbus, Ohio, United StatesRecruiting

+ 72 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT04973605