Condition: T-cell Acute Lymphoblastic Leukemia · T-Cell Acute Lymphoblastic Lymphoma · Sponsor: New York Medical College
A Phase I trial to determine the safety of targeted immunotherapy with daratumumab (DARA) IV after total body irradiation (TBI)-based myeloablative conditioning and allogeneic hematopoietic cell transplantation (HCT) for children, adolescents, and young adults (CAYA) with high risk T-cell acute lymphoblastic leukemia (T-ALL) or T-cell lymphoblastic lymphoma (T-LLy). Pre- and post-HCT NGS-MRD studies will be correlated with outcomes in children, adolescents, and young adults with T-ALL undergoing allogeneic HCT and post-HCT DARA treatment. The study will also evaluate T-cell repertoire and immune reconstitution prior to and following DARA post-HCT treatment and correlate with patient outcomes.
This description comes directly from the study's public registry record.
Lauren Harrison, RN, MSN · 6172857844 · lauren_harrison@nymc.edu
Erin Morris, RN · 7149645359 · erin_morris@nymc.edu
Always discuss trial participation with your own doctor first.
| Phoenix Children's Hospital | Phoeniz, Arizona, United States | Not Yet Recruiting |
| Loma Linda University Children's Hospital | Loma Linda, California, United States | Recruiting |
| University of California | Los Angeles, California, United States | Not Yet Recruiting |
| University of California | San Francisco, California, United States | Recruiting |
| Children's Hospital Colordao | Aurora, Colorado, United States | Not Yet Recruiting |
| Children's National Medical Center | Washington D.C., District of Columbia, United States | Not Yet Recruiting |
| University of Florida | Gainsville, Florida, United States | Recruiting |
| John Hopkins All Children's Hospital | St. Petersburg, Florida, United States | Not Yet Recruiting |
| Riley Children's Hospital | Indianapolis, Indiana, United States | Recruiting |
| Boston Children's Hospital | Boston, Massachusetts, United States | Recruiting |
| Helen DeVos Children's Hospital | Grand Rapids, Michigan, United States | Recruiting |
| New York Medical College | Vallhala, New York, United States | Recruiting |
+ 4 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT04972942