● Recruiting

A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours

Condition: Salivary Gland Tumor · Urothelial Carcinoma · Ovarian Carcinoma · Sponsor: Avacta Life Sciences Ltd

PhasePhase 1

Planned participants158

Who can joinAll sexes, 18 Years to no upper limit

Healthy volunteersNo

About this study

This is a first-in-human (FIH), Phase 1 open-label, multicentre dose escalation study investigating AVA6000 monotherapy administered intravenously in patients with locally advanced (unresectable) or metastatic solid tumours that are likely to be FAP positive. The study consists of an initial Phase 1a dose escalation portion and a subsequent Phase 1b dose expansion portion upon completion of the dose escalation portion.

This description comes directly from the study's public registry record.

Talk to the study team

Avacta Life Sciences · +44 (0)20 3911 0353 · clinicaltrials@avacta.com

Always discuss trial participation with your own doctor first.

Locations (9)

Memorial Sloan Kettering Cancer Center	New York, New York, United States	Recruiting
University of Texas MD Anderson Cancer Center	Houston, Texas, United States	Recruiting
Fred Hutchinson Cancer Center	Seattle, Washington, United States	Recruiting
The Beatson West of Scotland Cancer Centre, NHS Greater Glasgow & Clyde	Glasgow, United Kingdom	Recruiting
St James's University Hospital, The Leeds Teaching Hospitals NHS Trust	Leeds, United Kingdom	Recruiting
The Royal Marsden, NHS Foundation Trust	London, United Kingdom	Recruiting
The Christie NHS Foundation Trust	Manchester, United Kingdom	Recruiting
The Freeman Hospital, Newcastle-upon-Tyne NHS Foundation Trust	Newcastle upon Tyne, United Kingdom	Recruiting
Weston Park Cancer Centre, Sheffield Teaching Hospitals NHS Foundation Trust	Sheffield, United Kingdom	Not Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT04969835