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Study identifier: NCT04969315 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

TT-10 (PORT-6) and TT-4 (PORT-7) as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors

Condition: Renal Cell Cancer · Castrate Resistant Prostate Cancer · Non Small Cell Lung Cancer  ·  Sponsor: Portage Biotech

PhasePhase 1/Phase 2
Planned participants90
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate TT-10, TT-4 and TT-10 + TT-4, (Dual Blockade) in participants with advanced selected solid tumors, who have failed or are not eligible for standard of care. The main questions it aims to answer are: 1. To evaluate the safety and tolerability of TT-10, TT-4 and TT-10 + TT-4, (Dual Blockade) 2. To determine the maximum tolerated dose or the recommended phase 2 dose of TT-10, TT-4 and TT-10 + TT-4, (Dual Blockade) 3. To obtain a preliminary estimate of efficacy of TT-10, TT-4 and TT-10 + TT-4, (Dual Blockade) in advanced solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Desa Rae E Stanton-Pastore, MS  ·  1585-305-3850  ·  desi@portagebiotech.com; drpastore@cyncado.com

Always discuss trial participation with your own doctor first.

Locations (3)

USC Norris Comprehensive Cancer CenterLos Angeles, California, United StatesRecruiting
Norton Cancer InstituteLouisville, Kentucky, United StatesRecruiting
The University of Texas MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04969315