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Study identifier: NCT04968834 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Genomically Profiling, Collecting, Archiving and Distributing Hematologic Malignancy Specimens

Condition: Leukemia · Myelodysplastic Syndromes · Myeloproliferative Syndrome  ·  Sponsor: Dana-Farber Cancer Institute

PhaseN/A
Planned participants300
Who can joinAll sexes, N/A to 30 Years
Healthy volunteersNo

About this study

This research study is a genomic profiling and repository study for children and young adults who have leukemia, myelodysplastic syndrome (MDS) or myeloproliferative syndrome (MPS). Genes are the part of cells that contain the instructions which tell cells how to make the right proteins to grow and work. Genes are composed of DNA letters that spell out these instructions. Genomic profiling helps investigators understand why the disease develops and the instructions that led to its development. Understanding the genetic factors of the disease can also help investigator understand why the disease of some people can respond to certain therapies differently than others. The genomic profiling will be performed using bone marrow and blood samples that either have already been obtained during a previous clinical procedure or will be obtained at the time of a scheduled clinical procedure. Studying the genetic information in the cells of these samples will provide information about the origin, progression, and treatment of leukemia and myeloproliferative syndromes and myelodysplastic syndrome. Storing the bone marrow and blood samples will allow for additional research and genomic assessments to be performed in the future.

This description comes directly from the study's public registry record.

Talk to the study team

Yana Pikman, MD  ·  (617) 632-4754  ·  yana_pikman@dfci.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (8)

Connecticut Children's Medical CenterHartford, Connecticut, United StatesRecruiting
Maine Medical CenterPortland, Maine, United StatesRecruiting
Boston Children's HospitalBoston, Massachusetts, United StatesActive Not Recruiting
Dana Farber Cancer InstituteBoston, Massachusetts, United StatesActive Not Recruiting
Dartmouth-HitchcockLebanon, New Hampshire, United StatesRecruiting
Albany Medical CenterAlbany, New York, United StatesRecruiting
Lifespan Cancer InstituteProvidence, Rhode Island, United StatesRecruiting
University of Vermont Medical CenterBurlington, Vermont, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04968834