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Study identifier: NCT04968808 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Timing of FFR-guided PCI for Non-IRA in NSTEMI and MVD (OPTION-NSTEMI)

Condition: Myocardial Infarction, Acute · Multi-Vessel Coronary Artery Stenosis · Multi Vessel Coronary Artery Disease  ·  Sponsor: Chonnam National University Hospital

PhaseNA
Planned participants1014
Who can joinAll sexes, 19 Years to no upper limit
Healthy volunteersNo

About this study

Many patients with non-ST-segment elevation myocardial infarction (NSTEMI) have multivessel coronary artery disease (MVD), which is associated with poor clinical outcomes. However, there have been few studies regarding revascularization strategy in patients with NSTEMI and MVD. Therefore, we planned to perform prospective, open-label, randomized trial to evaluate the efficacy and safety of immediate complete revascularization (percutaneous coronary intervention \[PCI\] for both infarct-related artery \[IRA\] and non-IRA during index PCI) compared to staged PCI strategy of non-IRA (PCI for IRA followed by non-IRA PCI after several days). PCI procedure at non-IRA with diameter stenosis between 50 and 69% should be conducted with the aid of fractional flow reserve (FFR), and non-IRA with diameter stenosis ≥ 70% will be revascularized without FFR.

This description comes directly from the study's public registry record.

Talk to the study team

Min Chul Kim, MD  ·  82-62-220-6578  ·  kmc3242@hanmail.net

Always discuss trial participation with your own doctor first.

Locations (1)

Chonnam National University HospitalGwangju, South KoreaRecruiting

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Source record: clinicaltrials.gov/study/NCT04968808