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Study identifier: NCT04954599 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase 1/2 Clinical Trial of CP-506 (HAP) in Monotherapy or With Carboplatin or ICI

Condition: Unspecified Adult Solid Tumor, Protocol Specific  ·  Sponsor: Maastricht University Medical Center

PhasePhase 1/Phase 2
Planned participants126
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A modular, first time in human, open label, multiple dose, accelerated escalation with cohort expansion study of the safety and pharmacokinetics of intravenous infusion of CP-506, a tumor agnostic Hypoxia Activated Prodrug in patients with HRD/FAD solid tumours or tumor types with high incidence of HRD/FAD in monotherapy or in combination with carboplatin or patients with solid tumour and oligoprogressive disease receiving immune checkpoint inhibitors (ICI): a phase I-IIa clinical trial

This description comes directly from the study's public registry record.

Talk to the study team

Ludwig Dubois, PhD  ·  +31433882909  ·  ludwig.dubois@maastrichtuniversity.nl

Always discuss trial participation with your own doctor first.

Locations (5)

Institut Jules BordetBrussels, BelgiumNot Yet Recruiting
UZ GentGhent, BelgiumNot Yet Recruiting
Academisch Ziekenhuis Maastricht (Leading Centre)Maastricht, Limburg, NetherlandsRecruiting
Erasmus MCRotterdam, NetherlandsRecruiting
Institut Vall d'HebronBarcelona, SpainNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT04954599