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Study identifier: NCT04951622 Synced from ClinicalTrials.gov · July 27, 2026
● Recruiting

A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

Condition: Myasthenia Gravis  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 3
Planned participants199
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the efficacy and safety of nipocalimab compared to placebo in participants with generalized myasthenia gravis (gMG). The purpose of the subcutaneous substudy is to evaluate how well it works in the body (pharmacodynamic \[PD\]) when given as an injection under the skin (subcutaneous) compared to when given through a vein (intravenous) in participants with gMG.

This description comes directly from the study's public registry record.

Talk to the study team

Study Contact  ·  844-434-4210  ·  Participate-In-This-Study1@its.jnj.com

Always discuss trial participation with your own doctor first.

Locations (112)

Neuromuscular Research Center and ClinicParadise Valley, Arizona, United StatesRecruiting
HonorHealth NeurologyScottsdale, Arizona, United StatesCompleted
University of Southern CaliforniaLos Angeles, California, United StatesCompleted
Stanford UniversityPalo Alto, California, United StatesCompleted
Care Access ResearchPasadena, California, United StatesRecruiting
University of Colorado Anschutz Medical CampusAurora, Colorado, United StatesRecruiting
Yale New Haven HospitalNew Haven, Connecticut, United StatesRecruiting
FM Clinical Research, LLC South Florida Neurology Associates, P. A.Boca Raton, Florida, United StatesRecruiting
University of Florida Health JacksonvilleJacksonville, Florida, United StatesCompleted
Medsol Clinical Research Center IncPort Charlotte, Florida, United StatesRecruiting
University of South FloridaTampa, Florida, United StatesRecruiting
Augusta UniversityAugusta, Georgia, United StatesCompleted

+ 100 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04951622