Condition: Brain Injury Traumatic Moderate · Brain Injury Traumatic Severe · Post Traumatic Epilepsy · Sponsor: Hospital Sirio-Libanes
One of the most important neurological consequences following Traumatic Brain Injury (TBI) is the development of post traumatic epilepsy (PTE). Nevertheless, there is still no effective therapeutic intervention to reduce the occurrence of PTE. In previous studies with animals models of epilepsy, the biperiden decreased the incidence and intensity of spontaneous epileptic seizures besides delaying their appearance. The aim of this study is the evaluation of biperiden as antiepileptogenic drug to prevent PTE and also the determination of side effects, evaluating its cost-effectiveness in patients with moderate and severe TBI.
This description comes directly from the study's public registry record.
Eliana Garzon, MD, PhD · +55 (11) 98206-2308 · eliana.garzon@hsl.org.br
Maira L Foresti, PhD · + 55(11) 958673803 · mairalforesti@gmail.com
Always discuss trial participation with your own doctor first.
| Instituto Doutor José Frota | Fortaleza, Ceará, Brazil | Not Yet Recruiting |
| Santa Casa de Misericórdia de Sobral | Sobral, Ceará, Brazil | Recruiting |
| Hospital Estadual Urgencia e Emergencia -HEUE | Vitória, Espírito Santo, Brazil | Not Yet Recruiting |
| Hospital São Rafael | Salvador, Estado de Bahia, Brazil | Recruiting |
| Associação Beneficente Santa Casa de Campo Grande | Campo Grande, Mato Grosso do Sul, Brazil | Recruiting |
| Hospital São Vicente de Paulo | Passo Fundo, Rio Grande do Sul, Brazil | Active Not Recruiting |
| Hospital das Clínicas da Faculdade de Medicina da Universidade de Ribeirão Preto | Ribeirão Preto, São Paulo, Brazil | Recruiting |
| Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo | São Paulo, São Paulo, Brazil | Recruiting |
| Hospital Sirio-Libanes | São Paulo, Brazil | Recruiting |
| Hospital São Paulo, Universidade Federal de São Paulo | São Paulo, Brazil | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT04945213