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Study identifier: NCT04938765 Synced from ClinicalTrials.gov · July 28, 2026
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Effect of Magnesium Sulfate Bolus on Intraoperative Neuromonitoring

Condition: Intraoperative Neurophysiological Monitoring · Magnesium Sulfate  ·  Sponsor: Loma Linda University

PhasePhase 4
Planned participants50
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

Magnesium Sulfate(MgSo4) is increasingly being used as part of the multimodal pain regimen in the perioperative period. The intraoperative neurophysiological monitoring (IONM) is utilized in complex spine and cranial surgeries to assess the functional integrity of the neural pathways. The effect of Magnesium sulfate on IONM has not been studied. This is a prospective, double blind, randomized placebo controlled trial to study the effect of Magnesium sulfate bolus on the amplitude and latency of somatosensory(SSEPs) and motor evoked potentials(MEPs) in patients undergoing surgery requiring IONM.

This description comes directly from the study's public registry record.

Talk to the study team

Rashmi Vandse, MD  ·  9095584000  ·  rvandse@llu.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Loma linda University Medical CenterLoma Linda, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04938765