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Study identifier: NCT04938349 Synced from ClinicalTrials.gov · July 28, 2026
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Dual Task Perturbation Training for OAwMCI

Condition: Mild Cognitive Impairment · Old Age; Debility  ·  Sponsor: University of Illinois at Chicago

PhaseNA
Planned participants142
Who can joinAll sexes, 55 Years to no upper limit
Healthy volunteersYes

About this study

Studies have determined that compared to cognitively intact older adults (CIOA), older adults with mild cognitive impairment (OAwMCI) exhibit more pronounced balance and gait impairments which lead to an increased risk of falls and mobility decline. Such impairments are evident during dual-tasking (i.e., simultaneous performance of cognitive and motor task) and OAwMCI have demonstrated an increased cognitive-motor interference (deteriorated performance of either or both cognitive/motor task). Furthermore, our preliminary laboratory findings indicate that compared to CIOA, OAwMCI in response to large-magnitude treadmill perturbations exhibits poor reactive responses (first line of defense against balance loss) and are unable to modulate their responses as the magnitude of perturbation increases. Despite that conventional exercise methods offer beneficial effects; they comprise of self-initiated task-specific exercises and may not focus on training reactive responses. Additionally, due to the presence of subtle balance and gait deficits, clinical measures used may not be sensitive enough to determine the risk of fall post-training. Furthermore, these training methods incorporate multiple sessions due to which adherence to exercise training is difficult with only a fraction of the older adults benefiting from it. Therefore, it is essential to incorporate a task-specific strategy that promotes factors associated with falling like balance control, muscular responses, coordination …

This description comes directly from the study's public registry record.

Talk to the study team

Tanvi S Bhatt  ·  312-355-4443  ·  tbhatt6@uic.edu

Lakshmi Kannan  ·  312-413-3175  ·  lkanna2@uic.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Illinois at ChicagoChicago, Illinois, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04938349