Condition: Acute Coronary Syndrome · Percutaneous Coronary Intervention · Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
The MATE study is a randomized, multicenter, open-label, investigator-initiated clinical trial aimed to evaluate efficacy and safety of sequential monotherapy of ticagrelor and clopidogrel in patients with acute coronary syndrome (ACS) after coronary intervention. Standard DAPT of aspirin plus ticagrelor will be given for the first 1 month after PCI. After 1 month, event-free subjects will be randomized at 1:1 ratio into receiving standard DAPT (DAPT) until 12months , or switch to ticagrelor monotherapy for another 5 months , and further de-escalated to monotherapy of clopidogrel for the last 6 months(SAPT).
This description comes directly from the study's public registry record.
Heyang Wang, MD · 86 0571-87783759 · whysmmu@126.com
Changling Li, MD · +86 0571 89713104 · HREC2013@126.com
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| 2nd Affiliated Hospital, School of Medicine at Zhejiang University | Hangzhou, Zhejiang, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04937699