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Study identifier: NCT04936607 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

ImproviNg rEnal Outcomes Following Coronary angiograPhy and/or percuTaneoUs coroNary intErventions

Condition: Contrast-Induced Acute Kidney Injury  ·  Sponsor: Montreal Heart Institute

PhaseNA
Planned participants1158
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The NEPTUNE triple-blind, active-placebo, adaptive, pragmatic, randomized trial aims to evaluate the effectiveness of a new intra-venous hydration strategy guided by left ventricular end-diastolic pressure (LVEDP), amount of contrast used, and baseline renal function, to prevent contrast-induced acute kidney injury (CI-AKI) and patient-oriented clinical endpoints in all-comer patients undergoing coronary angiogram and/or percutaneous coronary intervention (PCI).

This description comes directly from the study's public registry record.

Talk to the study team

Guillaume Marquis-Gravel, MD, MSc  ·  (514) 376-3330  ·  guillaume.marquis.gravel@umontreal.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Montreal Heart InstituteMontreal, Quebec, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT04936607