Condition: Blood Pressure · Diabetes · Obesity · Sponsor: University of Kansas Medical Center
The purpose of this study is to examine the hypothesize that 4 weeks of sympathetic nerve activity (SNA) inhibition (oral clonidine) will cause a significant reduction in circulating blood concentrations and endothelial cell expression of inflammatory markers (e.g., TNF-α, IL-6). Our study is a prospective study using a randomized, double-blinded design to test 4 weeks of SNA blockade (oral clonidine) compared with a BP-lowering control condition (diuretic, hydrochlorothiazide) or a placebo.
This description comes directly from the study's public registry record.
Seth W Holwerda, Ph,D · 9729223230 · sholwerda@kumc.edu
Davina A Clonch · 9132266009 · dclonch@kumc.edu
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| University of Kansas Medical Center | Kansas City, Kansas, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04934228