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Study identifier: NCT04931225 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

LANdiolol MIcrocirculatory Effects During Septic chOc (MILANOS)

Condition: Septic Shock  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhasePhase 3
Planned participants44
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The objectives of this study are to evaluate the effect of continuous intravenous Landiolol injection (from 0.5 to 10 µg/kg/min during 12 hours ) up to a 15% decrease in Heart Rate (HR) on microcirculatory vascular reactivity vs. usual tachycardia management and evaluate the hemodynamic effects of Landiolol vs. usual management in patients with septic shock.

This description comes directly from the study's public registry record.

Talk to the study team

Hafid AIT-OUFELLA, Professor  ·  01 49 28 23 15  ·  hafid.aitoufella@aphp.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Intensive care department, Hôpital Saint AntoineParis, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT04931225