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Study identifier: NCT04925609 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Brigatinib in Pediatric and Young Adult Patients With ALK+ ALCL, IMT or Other Solid Tumors

Condition: Anaplastic Large Cell Lymphoma, ALK-Positive · Inflammatory Myofibroblastic Tumor · Other Solid Tumor  ·  Sponsor: Princess Maxima Center for Pediatric Oncology

PhasePhase 1/Phase 2
Planned participants65
Who can joinAll sexes, 1 Year to 25 Years
Healthy volunteersNo

About this study

This is an open-label, phase I-II dose-escalation and expansion study designed to define the recommended dose of brigatinib as monotherapy in pediatric and young adult patients with ALK+ ALCL, IMT or other solid tumors and to evaluate the pharmacokinetics (PK), (long-term) safety, and efficacy of brigatinib in these children.

This description comes directly from the study's public registry record.

Talk to the study team

Maaike Boonstra  ·  +31642055985  ·  m.boonstra@prinsesmaximacentrum.nl

Gertruud Bakker  ·  +31889727272  ·  G.C.M.Bakker-7@prinsesmaximacentrum.nl

Always discuss trial participation with your own doctor first.

Locations (2)

Institut Gustave RoussyParis, FranceRecruiting
Princess Máxima Center for Pediatric OncologyUtrecht, Utrecht, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT04925609