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Study identifier: NCT04925492 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

PET Imaging of Vaso-Occlusive Crisis (VOC) in SCD

Condition: Sickle Cell Disease  ·  Sponsor: Enrico Novelli

PhasePhase 1
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to find objective biomarkers of vaso-occlusion (blood vessel blockage) in people with SCD. Using information from earlier studies and work being done, researchers have developed a strategy to image VOC, using positron emission tomography (PET). The ability to see and measure VOC in SCD patients can help patient care, by showing when and how a VOC is occurring or going to occur. Studying this method will also help in future drug research, as it will allow researchers to deliver promising new medications that target hyper-adhesion and sickling in people with SCD.

This description comes directly from the study's public registry record.

Talk to the study team

Jude Jonassaint, RN  ·  919-219-7481  ·  jonas@pitt.edu

Leticia Candra, BA  ·  LEC117@pitt.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UPMCPittsburgh, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04925492