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Study identifier: NCT04924868 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Ursodeoxycolic Acid for the Prevention of Relapsing Complications After Gallstone Acute Pancreatitis

Condition: Acute Pancreatitis Due to Gallstones  ·  Sponsor: Hospital General Universitario de Alicante

PhasePhase 3
Planned participants332
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Acute pancreatitis is a common disease (3rd cause of hospital admission for digestive causes), which is associated with significant patient suffering, a 2-4% probability of death and considerable healthcare costs. Sixty percent of acute pancreatitis are due to the presence of stones in the gallbladder. The risk of suffering another acute biliary pancreatitis (ABP, that is to say, pancreatitis due to gallstones) or of other biliary complications in the following weeks or months is high (20% or greater) if measures are not taken to avoid it, being surgical removal of the gallbladder the most effective. Unfortunately, most Spanish centers have a surgical waiting list that makes gallbladder surgery unfeasible in a period of less than weeks or months, which is why readmission for biliary problems derived from the stones is a common problem. This, of course, causes danger and great stress and anger for patients affected by these complications on the waiting list, damaging their relationship with the health system and it is linked to increased cost. In addition, there is a very vulnerable group, those patients who due to age or serious diseases cannot undergo gallbladder surgery but have a high probability of suffering biliary problems due to the stones they have. Ursodeoxycholic acid (UDCA) is very safe drug which is used to dissolve gallstones, but its role in preventing biliary complications after ABP has not been studied adequately so it is not frequently used. Our objective is…

This description comes directly from the study's public registry record.

Talk to the study team

Alicia Vaillo  ·  (+34) 661302932  ·  vailloalicia@gmail.com

Always discuss trial participation with your own doctor first.

Locations (18)

Hospital Clínico Universitario de SantiagoSantiago de Compostela, A coruña, SpainNot Yet Recruiting
Hospital General Universitario de AlicanteAlicante, Alicante, SpainRecruiting
Hospital General Universitario de ElcheElche, Alicante, SpainNot Yet Recruiting
Hospital Univerisitario Vall D´HebronBarcelona, Barcelona, SpainNot Yet Recruiting
Hospital de BellvitgeL'Hospitalet de Llobregat, Barcelona, SpainNot Yet Recruiting
Consorci Corporació Sanitària Parc Taulí de SabadellSabadell, Barcelona, SpainNot Yet Recruiting
Hospital Universitario Marqués de ValdecillaSantander, Cantabria, SpainNot Yet Recruiting
Hospital Clínio San CecilioGranada, Granada, SpainNot Yet Recruiting
Hospital Ramon y CajalMadrid, Madrid, SpainRecruiting
Hospital Costa del Sol,Marbella, Málaga, SpainRecruiting
Clinica Unversidad de NavarraPamplona, Navarre, SpainRecruiting
Complejo Hospitalario de OurenseOurense, Ourense, SpainNot Yet Recruiting

+ 6 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04924868