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Study identifier: NCT04908579 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Efficacy of Preventive Ketamine on Postoperative Pain

Condition: Postoperative Pain  ·  Sponsor: Ain Shams University

PhasePhase 4
Planned participants90
Who can joinAll sexes, 21 Years to 60 Years
Healthy volunteersNo

About this study

* Although bariatric surgery is mainly performed laparoscopically, analgesic optimization is still essential to reduce complications and to improve the patients' comfort. In laparoscopic sleeve gastrectomy, the intraoperative peritoneal instillation of bupivacaine hydrochloride (30 ml, 0.25%) was known to be safe and effective in reducing postoperative pain, nausea, and vomiting. * Furthermore, usage of ketamine both as a pre and post-operative pain management is well established. Ketamine can be used solely or in combination with other co-adjuvant drugs, increasing their efficacy. Many therapeutic properties of ketamine have been attributed to its antagonism mechanism to N-Methyl-D-aspartate receptors.

This description comes directly from the study's public registry record.

Talk to the study team

Ibrahim Mamdouh Esmat  ·  01001241928  ·  ibrahim_mamdouh@med.asu.edu.eg

Always discuss trial participation with your own doctor first.

Locations (1)

Ain-Shams University HospitalsCairo, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT04908579