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Study identifier: NCT04901234 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Adaptive RadioTherapy for OroPharynx Cancer

Condition: Oropharynx Cancer · Radiotherapy; Complications · Radiotherapy Side Effect  ·  Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

PhasePhase 2
Planned participants120
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase II randomized trial, where patients with histologically proven squamous cell carcinoma of oropharynx that have primary tumor (T3 - T4) in place, treated with curative intent chemoradiation, will be randomized to systematic mid-treatment MRI-based radiotherapy adaptation vs. standard of care. The primary objective is to compare patient-rated dysphagia (as assessed by the MD Anderson Dysphagia Inventory composite score at 6 months post-treatment in patients undergoing routine mid-treatment MR-guided radiotherapy adaptation vs. in patients receiving the current standard of care.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (2)

Austin HealthMelbourne, AustraliaNot Yet Recruiting
Centre Hospitalier de l'Université de MontréalMontreal, Quebec, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT04901234