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Study identifier: NCT04896281 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Phenylalanine-free Diet for Patients With Secondary Hyperphenylalaninemia in ICU

Condition: Non-Phenylketonuric Hyperphenylalaninemia  ·  Sponsor: Chang Gung Memorial Hospital

PhaseNA
Planned participants100
Who can joinAll sexes, 20 Years to no upper limit
Healthy volunteersNo

About this study

Hyperphenylalaninemia is not only present in patients with congenital phenylketonuria. In adults with critical illness, hyperphenylalaninemia is noted in some patients and is associated with high mortality rate. Hyperphenylalaninemia can cause metabolic acidosis, brain dysfunction, and metabolic disturbance. The investigators would like to see whether the phenylalanine-free milk for congenital phenylketonuria is also effective in lowering the blood phenylalanine concentrations in patients with critical illness in intensive care unit and hyperphenylalaninemia.

This description comes directly from the study's public registry record.

Talk to the study team

CHAO-HUNG WANG, MD, PhD  ·  0224313131  ·  bearty@cgmh.org.tw

MIN-HUI LIU, RN, PhD  ·  0224313131  ·  min4108@cgmh.org.tw

Always discuss trial participation with your own doctor first.

Locations (1)

Chang Gung Memorial HospitalKeelung, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT04896281