← Eichor
Study identifier: NCT04892654 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy of Doravirine + Dolutegravir Dual Therapy in the Context of Antiretroviral Therapy Switch

Condition: HIV-1-infection  ·  Sponsor: Chelsea and Westminster NHS Foundation Trust

PhasePhase 3
Planned participants150
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Combination antiretroviral therapy (cART) HIV treatments are associated with increased quality of life, and a normalisation of life expectancy in people living with HIV. However, long-term use of cART can lead to side-effects through exposure to drug-related toxicity. For this reason researchers are interested in looking at alternative therapies that might expose patients to fewer and less severe side effects while providing the same quality of care as antiretroviral therapies most often used to treat HIV. The purpose of this study is to investigate if the study drug combination that is being tested (doravirine + dolutegravir) is safe compared with other triple cART regimens.

This description comes directly from the study's public registry record.

Talk to the study team

Research Regulatory Compliance Manager  ·  020 3315 6825  ·  chelwest.research@nhs.net

Always discuss trial participation with your own doctor first.

Locations (3)

Mortimer Market CentreLondon, United KingdomRecruiting
Chelsea & Westminster Hospital NHS Foundation TrustLondon, United KingdomRecruiting
Imperial College Healthcare NHS TrustLondon, United KingdomRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT04892654